Five ordinary people are brought together to form one extraordinary team of Alphas -- people with the unique power to stretch the capabilities of the human mind giving them superhuman physical and mental abilities. Operating within the Defense Criminal Investigation Service of the U.S. Department of Defense and led by preeminent neurologist and psychiatrist Dr. Lee Rosen, an expert in Alpha phenomena, the team investigates cases that point to others with Alpha abilities. As they work against the clock to solve this new brand of crime, they must prevent their own personality differences and disparate backgrounds from interfering with their ultimate mission to catch the enemy.
