Television reporter Angela Vidal (Jennifer Carpenter) and her cameraman (Steve Harris) are
assigned to spend the night shift with a Los Angeles Fire Station. After a routine 911 call takes
them to a small apartment building, they find police officers already on the scene in response
to blood curdling screams coming from one of the apartment units. They soon learn that a
woman living in the building has been viciously attacked by something unknown. After a few of
the residents are also attacked, they try to escape with the news crew in tow, only to find that
the CDC has quarantined the building. Phones, internet, televisions and cell phone access have
been cut-off, and officials are not relaying information to those locked inside. When the
quarantine is finally lifted, the only evidence of what took place is the news crew's videotape.