Talaash follows inspector Surjan Singh Shekhawat (Aamir Khan), who is tackling the accidental death of a film star Armaan Kapoor (Vivan Bhatena). As Shekhawat unfolds the strange case, he gets entangled in a drama that has more to it than meets the eye. Meanwhile, his personal life suffers as he reels under the repercussions of an almost-broken marriage with Roshni (Rani Mukerji), and comes face-to-face with his suppressed grief of losing his only child.
While trying to investigate the case, Shekhawat meets a sex worker Rosie (Kareena Kapoor), who helps him fight his inner demons and also helps him with his enquiry about the accident. How Shekhawat solves the case and revives his relationship with his wife forms the crux of the story.
